Job title: Senior Scientist (PCR team)Reports to: PCR Team LeaderLocation: Manchester Science ParkContract Type: Full-time, PermanentSalary & Benefits: Competitive Salary + Benefits PackageAbout Yourgene Health:Yourgene Health is a leading integrated technologies and services business, enabling the delivery of genomic medicine.
The group works in partnership with global leaders in DNA technology to advance diagnostic science.Yourgene primarily develops, manufactures, and commercialises simple and accurate molecular diagnostic solutions, for reproductive health, precision medicine and infectious diseases.
The Group's flagship in vitro diagnostic products include non -invasive prenatal tests (NIPT) for Down's Syndrome and other genetic disorders, Cystic Fibrosis screening tests, invasive rapid aneuploidy tests and DPYD genotyping.Yourgene has a range of innovative DNA sample preparation platforms, powered by Ranger Technology, the Yourgene LightBench and Yourgene QS250, ideal for cell free DNA applications in NIPT and oncology including liquid biopsy.Yourgene also has a global laboratory service network equipped to be a full life-cycle partner for clinical, research and pharmaceutical organisations to support partners at the preclinical, clinical, and post market stage to develop, manufacture, obtain regulatory approval and commercialise new products and services.
In addition, Yourgene offers and NIPT and high throughput Covid testing service.Yourgene Health is headquartered in Manchester, UK with facilities in Taipei, Singapore, the US and Canada.Our Culture:Yourgene is a growing, vibrant and exciting place to work, we are looking for committed driven individuals to be part of our next growth journey.
Our culture is described by our employee's as collegiate, friendly, professional, innovative, open and fast paced.
We have nay social and well-being initiatives run by our Social Huddle that keep our sense of community alive during challenging times that the pandemic has thrown our way.
At Yourgene we focus on putting values led programmes in place to ensure that we can attract, retain and develop our people.
We want our people to have a career with Yourgene and we ensure that they are recognised and rewarded for their achievements and commitment, everyone plays a critical role in our growth journey.Description of role:Yourgene Health, part of the Novacyt Group, are recruiting for a Senior Scientist within our PCR Diagnostics Team based at Manchester Science Park.
The Senior Scientist will work alongside the PCR Team Leader to lead the tactical delivery and development of PCR based in vitro diagnostic products and services.Overall responsibility:The Senior Scientist will provide scientific expertise and technical leadership on development projects ensuring tactical planning is performed effectively and consider problems at a system level.
In addition, the Senior Scientist will design and develop in vitro PCR diagnostic products/ services for use in a range of applications to high quality and in a timely fashion.
The scope will include PCR products developed in line with ISO 13485 and IVDR regulations.Key areas of responsibility:Perform laboratory based technology development using molecular biology techniques including PCR and qPCRIndependently design and execute experimental laboratory proceduresWork collaboratively with others in the team, troubleshooting issues and suggesting next steps to resolve these whilst maintaining an innovative spiritAnalyse experimental results, providing detailed conclusions and identifying technical solutionsEffective management of required documentation in accordance with company Quality Management System and ISO 13485 regulationsProvides scientific expertise and technical leadership on projects, as well as planning tactical delivery in functional areaLead and participate in activities requiring cross functional collaboration, including leading complex projectsSupport the resource planning activities of Team Leaders and Project LeadersProvide expertise into the creation, maintenance and improvement of; Overall processSOPsProcess flows, standardized plans & reportsEnsure planning and reporting of studies and work-packages is accurate and detailedDesign effective and efficient studies involving; Accurate, efficient and timely documentationDeveloping and implementing protocols to show that tests meet acceptance criteriaData generation, ensuring integrity and organized data managementProvide accurate, concise and independent data interpretation, factoring in systems-level thinkingDetermining test parameters, such as output specificationsMeeting regulatory or other requirementsLead troubleshooting activities when technical issues ariseSupports the development of external relationships, including through for example, grant applications, KOLs and partnersSupports the identification of commercially and technically useful solutions for developmentEnsure own work meets regulatory & quality requirements (including compliance to SOPs, documentation using lab books, study plans, study reports and integrity of data)Ensure own work and that of junior staff is performed in line with company goalsProvide support and guidance to junior staffQualifications, Skills and Abilities:Degree or further degree in a life science such as molecular biology, biochemistry or geneticsTypically 7+ years of relevant industry experienceExperience in the development, verification and validation of molecular diagnostics assays in adherence with CE marking and/or Design Control Regulations, ideally within IVDR and ISO 13485 regulationsHands on experience with PCR based assays including proficiency in primer and probe design and the use of Bioinformatics software (e.G.
Geneious or equivalent)Analysis of data and interpretation of resultsCapable of independently performing experimental design and executionEnthusiasm, drive, thoroughness, diligence and a willingness to take personal responsibility to ensure that projects are successfulExcellent communication, presentation and interpersonal skillsGood organizational skills and thrives on working to tight deadlinesCan summarize scientific data in written form to effectively communicate plans, progress and ideas with Management, Peers or External AudiencesGood IT skills including Microsoft Office Suite and use of the statistical analysis software, JMPClosing Date:Sunday 19th January, 2025Yourgene Health is committed to encouraging equality, diversity and inclusion among our workforce.
The aim is for our workforce to be truly representative of all sections of society and for each employee to feel respected and able to give their best.