Senior Laboratory Research ScientistSalary for this Role: From £39,950 per annum, subject to skills and experience, with benefits.
Job Title: Senior Laboratory Research Scientist
Reports to: Aleksey Chudnovskiy
Closing Date: 29/Oct/2024 23.59 GMT
Job Description: The Role The role of a Senior Laboratory Research Scientist in the Crick is diverse and rewarding. The role covers a wide range of different functions and allows for continuity of lab operations. The role offers support to one or more scientific projects or programmes. Typical activities include:
Collaborating with other lab members on/ assisting other lab members with research projects.Providing experimental or technical support to other lab members.Providing technical expertise input for the development, refinement and troubleshooting of relevant novel methodologies.Undertaking own research project, designing, and executing experiments with strategic direction from the group leader.Managing long-term investigations and collaborations with other researchers.Participating in academic activities, including group meetings and journal clubs, seminars, and scientific meetings.Writing up findings for publication and completing revisions.Organisation and management of the laboratory, including maintaining laboratory databases, ordering of laboratory supplies, monitoring budgets, and routine maintenance of laboratory equipment.Training and supervising other lab members in key techniques and protocols, lab operations, and equipment use.Liaising with Science Operations and attending key quadrant meetings.Writing risk assessments and SOPs and providing safety guidance to lab members.The Research Group The laboratory of Tumour-Immune Communication has been established in early 2024. We study bidirectional interactions between cancer cells and the host immune system using synthetic and molecular biology, genetics, and immunology. This research delineates how interaction dynamics between tumour cells and immune cells influence each other, contributing to our understanding of tumour progression and antitumour immune response.
Research techniques used in the laboratory include: We utilize immunological, genetic, genomic, molecular and synthetic biology techniques to study tumour immunology.
Key responsibilities These include but are not limited to:
Developing new techniques and protocols that are critical to the laboratory.Assisting the group leader with daily tasks.Engaging in and advancing a variety of scientific projects.Fostering collaboration with different laboratories within the Crick.Instructing both current and new lab members in general protocols and techniques that are commonly used in the lab.Drafting, executing, and revising Safety Assessments.Creating, implementing, and revising mouse protocols.Managing the care of complex genetically modified mouse colonies.Overseeing lab management.Sharing experimental results and discoveries both within and beyond the Crick.Drafting manuscripts for publication.Filling in for the Group Leader when they are absent.Experience and Competencies The post holder should embody and demonstrate our core Crick values:
Bold; Open; Collegial Essential PhD in Immunology, Cancer Biology, Molecular Biology, or Cellular BiologyExtensive post-PhD experience in Immunology, Tumour Biology, Molecular Biology, or Cellular BiologyExperience in working with mouse tumour models, cell cultures, and flow cytometryExcellent communication skillsAbility to work independently and as part of a teamProven track record of writing scientific papers, as demonstrated by publications or manuscripts submitted to peer-reviewed journalsExperience in presenting data at scientific conferencesCapable of independently developing scientific research projectsCompetence in supervising other lab membersDesirable Proficiency in single-cell RNA sequencing using both droplet-based and plate-based methods.Genetic screening using CRISPRsProficiency in analysing single-cell RNA sequencing (scRNA-seq) data using Python and/or R.About Us At the Crick, we conduct research at the forefront of biomedical research. We combine rigour with an open and collaborative culture, and are outward-looking, reflecting our status as a partnership of six organisations aiming to pool knowledge, ideas and resources.
We aim to attract the most talented researchers and support them to tackle innovative research questions.
If you are interested in applying for this role, please apply via our website.
All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.
If you require a visa to work in the UK we will help support your application should you be successful.
Equality, Diversity & Inclusion We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level.
Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute's success.
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