Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle Toxin Conjugate (BTC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle Radio Conjugates (BRC) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle technology to develop therapies for diseases beyond oncology.
Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, MA USA.
Culture is key and all Bicycle employees actively embrace and role model our company values:
We are Dedicated to our Mission . You can't change the world if you don't have determination. We are One Team . We only succeed when we work together. Job Description The HR Operations Specialist is responsible for administrative and operational activities across the entire employee lifecycle with a key focus on candidate, employee and manager experience. They will act as the first point of contact for our employees, ensuring a comprehensive, efficient and high-quality HR service provision, maintaining HR systems and processes to a high standard, as well as assisting with a range of HR projects and initiatives.
This role will operate with a bias towards end-to-end lifecycle activities and administration including but not limited to onboarding, variation to terms, offboarding, HR systems & analytics, HR governance and compliance as well as payroll and benefits.
HR ADMINISTRATION, ACTIVITIES, ADVISORY SUPPORT & GOVERNANCE Produce standard and non-standard end-to-end employee lifecycle correspondence e.g. letters, offers of employment, contracts, changes in employment and circumstances. Manage end-to-end employee lifecycle processes and activities i.e. recruitment, hire, onboarding, changes, transfers, absence and offboarding, ensuring a seamless candidate and employee experience. Provide first line support as related to HR Operations, while always maintaining discretion and professionalism. Work alongside wider HR team to produce, establish and maintain Company documentation e.g. Employee Handbook, Principles, Policies and Guidance. Focus on simplification, streamlining and continuous improvement. Partner with key process stakeholders to drive consistency in ways of working across multiple sites, whilst recognizing when this needs to flex to meet the needs of the business; respecting local cultures and legislative differences. Partner with colleagues in Finance to submit all payroll change information, assisting with any queries that may arise ensuring deadlines are met. Partner with benefits advice providers, providing data for benefit enrolments and renewals and coordinating benefits communications to employees. Maintain efficient diary management for self and team as required, including confidential meetings, benefit sessions, travel and any other requests. Support other ad-hoc activities such as purchase orders, invoicing, and vendor management. As needed, support our Talent Acquisition team with all recruitment requirements and our L&D Lead with any learning and development activities. HR SYSTEMS & ANALYTICS Maintain efficient digitized filing systems aligned to GDPR, ensuring individual employee files are always up to date and compliant. Develop regular reporting structures and analytics capability, and look to build valuable insights to support or drive business activity and HR priorities, reporting and dashboarding. Ownership of data integrity ensuring accuracy and security, and that the system is being used effectively. Identify and action areas for process improvement and map process steps (with stakeholders). Continuous improvement of workflows, task lists and use of features within Hibob to deliver an efficient, streamlined and enjoyable employee and manager experience. EMPLOYEE ENGAGEMENT & COMMUNICATION Role model Bicycle culture and values and ensure they are reflected and embedded across all HR practices. Support content for office and Company-wide engagement activities that encourage collaboration. Identify opportunities to strengthen the employer brand and support Company objectives and culture across employee lifecycle. Create, develop and maintain HR communications on Hibob and other channels i.e., news posts, employee and manager self-service content. Qualifications Passion for people with a strong interest in administration, systems, analytics and 'getting it right, first time. Proactive, inquisitive, committed with a 'we win as one' attitude, as well as a growth & ownership mindset. High level of personal integrity, positive with high emotional resilience. Past experience with payroll and or benefits strongly preferred. Diplomatic and influential with the ability to build credible relationships with diverse audiences and communicate effectively at all levels across the business. Strong organizational skills with excellent attention to detail & accuracy. Problem solver who is solutions driven and able to suggest opportunities for continuous improvement and operational efficiency. Experience of working in a client facing HR team with a good understanding of HR operations, best practice, providing excellent and efficient customer service and awareness of employment law issues in UK & US. Working in a fast-paced, transformational and confidential environment. Managing and prioritizing workload with competing demands and priorities. Ability and willingness to work collaboratively within a team and a flair for working independently. Ability to deal with sensitive matters with confidence. Experienced user of HCM/HRIS software (implementation experience desirable) & proficient reporting and analytical skills. Skilled in Microsoft Packages e.g. Visio, Word, PowerPoint, Excel and Outlook. Additional Information State-of-the-art campus environment with on campus restaurant and Montessori nursery. Flexible working environment. Competitive reward including annual company bonus. 28 days annual leave in addition to bank holidays + option to buy up to 5 additional days annually. Employer contribution to pension (employee does not have to contribute). Life assurance cover 4x basic salary. Private Medical Insurance, including optical and dental cover. Enhanced parental leave policies. Group income protection. Employee assistance program. Health Cash Plan. Access to company subsidized gym membership. Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc. Cycle to work scheme. Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.
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