GBS diseases are a major cause of morbidity and mortality in humans.
The molecular basis and infection processes of these diseases remain to be fully determined.
We strive to decipher the molecular processes that drive GBS to cause adult invasive, principally the mechanisms utilised to evade and/or manipulate the immune responses.We are seeking a forward-thinking and passionate Research Technician to support our research exploring the host-pathogen interactions that shape adult invasive infections by the bacterial pathogen Streptococcus agalactiae (also known as Group B Streptococcus or GBS).This post is funded by an MRC grant awarded to , which aims to characterise the biological functions of the GBS and human CEACAM1 receptor interactions.
This will be achieved by utilizing biochemical and cellular infection approaches.
You will be supporting research that combines molecular, microbiological, cellular and tissue-infection based approaches to contribute to an advanced understanding of invasive GBS diseases.You will be based in the group of Alex McCarthy in the Centre for Bacterial Resistance Biology (CBRB), and in the Section of Molecular Microbiology within the Department of Infectious Diseases (DoID) at Imperial College London.You will support research that addresses questions on the functional properties on the interactions of GBS with human inhibitory receptors, and specifically how this may regulate anti-bacterial immune responses and promote bacterial infection.
You will be expected to perform routine work in the laboratory to help support its structure and research.You will have clear and timely communication with the researchers within the group and with others in the Department.
You will attend and actively contribute to relevant workshops, lab meetings, research seminars and conferences in Imperial and the wider community.
You may supervise undergraduate students.
We are looking for a highly motivated candidate with research interests in bacterial infection biology.
Applicants must demonstrate as part of their application, how they meet the essential criteria required of the post.You will hold a Masters degree in bacterial infection biology or host-pathogen interactions, or a closely related area.Hold a first-class Bachelors degree in biochemistryhave experience of performing research using techniques relevant to bacteriology, host-pathogen interactions and/or bacterial infection biology.have experience in a broad range of molecular biology, biochemical and/or cell biology techniques.have experience in handling and performing research with Group B Streptococcuspossess excellent verbal and written communication skills.enjoy working collaboratively.
form positive relationships with the research group and wider community.
The opportunity to contribute to innovation in bacterial infection biology.Training in complementary aspects of bacterial infection biology in the .The opportunity to collaborate with other researchers in the Group of .The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity.Grow your career: Gain access to Imperial's sector-leading as well as opportunities for promotion and progressionSector-leading salary and remuneration package (including 39 days off a year and generous pension schemes).